OxyBolin 250

Increase Athletic Effectiveness

Oxybolin 250 is formulated for:
Anyone who desires to build muscle and/or enhance athletic performance.
Any bodybuilder or athlete already taking anabolic steroids, HGH, and/or creatine supplements who wants to increase muscle growth.
Anyone who wants a supplement that will reinforce (rather than be redundant to) his or her current athletic supplement stack.
Athletes who stay away from androgen supplements (e.g., women), but still want to increase muscle growth.

As a group, ecdysteroids are naturally occurring, polyhydroxylated plant sterols that have a plethora of non-hormonal anabolic and ergogenic activities in the human body. Their structure is composed of three hexane (6 carbon) rings and one pentane (5 carbon) rings. The most biologically active form of the ecdysteroids is thought to be 20-EC and turkesterone, both of which are collected from Rhaponticum carthamoides. Selections of this potent plant have been approved by the Ministry of Public Health in the former Soviet Union over 20 years ago to be utilized for "raising the mental and physical working ability" as a pharmacological preparation.

Introduction 
Rhaponticum carthamoides (Willd.) Iljin, syn. Leuzea carthamoides (Willd.) DC, is a large perennial herb in the compositae family. Rhaponticum carthamoides is composed of a wood-like horizontal rhizome, multiple long, hard roots, and has potential of growing to a height of over six feet. Rhaponticum carthamoides grows in the pristine alpine and subalpine zones, and alpine meadows of Southern Siberia. The roots and rhizomes are the medicinal parts, with the biological activity acknowledged by phytoecdystone quantity, including ecdysterone.

Chemistry 
The principal constituents of the whole plant are ecdysteroids (5-beta-cholest-6-on-7-ene derivatives) and flavonoids. Also polyacetylenes and triterpenes have been detached from different parts of the plant (Girault et. al. 1984, Szendrei et. al. 1984, Varga et al. 1986 and 1990). Of the isolated compounds, only 20-hydroxyecdysone and Turkesterone are currently considered to perform as an important role in the action of this plant. (Syrov and Kurmukov 1976). The main flavonoides are 6-methoxy-kampferol, patuletin, isorhamnetin-glycoside and quercetin-5-glycoside. All leaf and root samples contained 20-hydroxyecdysone as a main compound of Rhaponticum carthamoides. The 20-hydroxyecdysone of the roots ranged from 0.7% to 2.0% being higher than that of the leaves.

The 20-hydroxyecdysone content of the leaves ranged between 0.006 and 0.10%. Based off the quantitative and qualitative data obtained experimentally, the ideal time for root collection of Rhaponticum carthamoides is at the end of August when the 20-hydroxyecdysone content is the highest.

The research on the effects of Rhaponticum carthamoides has been performed for the last 60 years on the whole plant extract with 20-Hydroxyecdysone and turkesterone being the principal active compounds. Ingested ecdysteroids survive exposure to gastric acid and are rapidly consumed into the enteric blood vessels. Excretion is primarily via the liver. More recent research has identified 8 ecdysterones, and has confirmed synergy in their partnered usage (Baltaev and Abubakirov 1987; Gorovits et al 1974; 1977). When using a powdered extract of Rhaponticum carthamoides ensure that it is standardized to 50-65% 20-Hydroxyecdysterone. This will establish that the extract possesses a potent amount of 20-EC and with a natural extraction process it should yield between 75% and 100% total Ecdysones or ecdysteroids. When properly extracted, Rhaponticum carthamoides should have 2 parts 20-Hydroxyecdysterone to 1 part total ecdysones or ecdysteroids. Rhaponticum carthamoides posesses a number of other biologically active compounds believed to perform in harmony with ecdysterones, imparting its unique adaptogenic qualities (Azizov and Seifulla 1998). It is high in flavanoids, sesquiterpene lactones, and polyines (Opletal et al 1997).

OxyBolin 250 & Protein 
In one study, a natural protein substance considered to favorably affect the muscle-fat ratio, as well as work capacity among athletes, was used in a partnership with RCE and compared to placebo (Lupandin 1991). In the partnered study, it was found that taking RCE combined with additional supplemental protein was supreme to accomplish the highest increase in work capacity in athletes. Of the athletes who acquired just protein, only a slight boost in muscle mass was noticed. Those who used a placebo lost a slight amount of lean muscle, while those who utilized protein plus ecdysterone, showed a 6-7% boost in lean muscle tissue with nearly a 10% drop in fat. No difference in hormonal parameters in those taking RCE was noted during the study period.


Supplement Facts:
Serving Size: 1 Tablet
Servings Per Container: 60

Amount Per Serving: 
Rhaponticum Carthamoides 98% Extract: 250mg
(including 20-hydroxyecdysterone, turkesterone, and ponasterone).

Proprietary Blend with Extend-Rx: 400mg
(6-keto-diosgenin, 7-keto-diosgenin, DHEA, beta-sitosterol 6,7 dihydroxy bergamotting, naringen, theobroma cocoa extract.

Other Ingredients:
Microcrystalline cellulose, dextrose, sodium starch glycolate, hydroxy propylmethylcellulose, magnesium stearate, stearic acid, silic, FD&C yellow #10.

Directions:
Take 1 tablet twice daily.